Understanding an Enlarged Heart (Cardiomegaly): Causes, Symptoms, and Treatment

The heart is one of the most critical organs in the human body, responsible for pumping blood throughout the system to supply oxygen and nutrients. While a healthy heart maintains its size relative to the individual, conditions can cause it to enlarge—a condition known as cardiomegaly or an enlarged heart.

An enlarged heart is not a disease but rather a symptom of an underlying issue. Understanding the causes, symptoms, diagnosis, and treatment options is vital for managing this condition and maintaining heart health.

What is Cardiomegaly?

Cardiomegaly refers to the enlargement of the heart, which can occur for various reasons. The term doesn’t describe a specific disease but refers to a physical change where the heart grows in size, often due to stress, damage, or overworking of the heart muscle.

The heart enlarges in two ways:

  1. Hypertrophy: The heart walls thicken, leading to less space within the chambers.
  2. Dilation: The chambers of the heart expand, making the walls thinner.

Both forms of enlargement may compromise the heart’s ability to pump blood efficiently, leading to further complications like heart failure.

What Causes an Enlarged Heart?

There are numerous factors that can lead to cardiomegaly, ranging from temporary conditions to chronic diseases. Here are some of the most common causes:

1. High Blood Pressure (Hypertension)

Persistent high blood pressure forces the heart to work harder to pump blood. Over time, this additional strain causes the heart muscle to thicken, enlarging the heart.

2. Heart Valve Disease

If one or more heart valves are not functioning correctly, it can cause blood to flow backward, putting extra pressure on the heart, which may cause it to expand to compensate for the inefficiency.

3. Coronary Artery Disease (CAD)

CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge.

4. Cardiomyopathy

Cardiomyopathy is a condition that affects the heart muscle, causing it to become enlarged, thick, or rigid. This condition often leads to heart failure, as the heart cannot effectively pump blood.

5. Arrhythmias (Irregular Heartbeats)

Persistent abnormal heart rhythms can disrupt the heart’s pumping efficiency, eventually causing it to enlarge to maintain blood flow.

6. Congenital Heart Defects

Some individuals are born with heart defects that cause parts of the heart to work harder, leading to enlargement over time.

7. Fluid Around the Heart (Pericardial Effusion)

Fluid buildup between the heart and the pericardium (heart lining) can make the heart appear enlarged in imaging, even if the heart muscle is not physically bigger.

8. Chronic Pulmonary Disease

Lung diseases like chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension, which in turn can cause the right side of the heart to enlarge, a condition known as cor pulmonale.

9. Anemia

Severe, untreated anemia can force the heart to pump more blood to compensate for the lower oxygen levels in the blood, potentially leading to enlargement.

10. Thyroid Disorders

Both hyperthyroidism (an overactive thyroid) and hypothyroidism (an underactive thyroid) can cause heart problems, including enlargement.

11. Excessive Alcohol or Drug Use

Long-term abuse of alcohol or certain drugs can weaken the heart muscle, resulting in cardiomyopathy and eventually cardiomegaly.

12. Pregnancy-Related Conditions

Conditions like peripartum cardiomyopathy can develop late in pregnancy or after delivery, causing the heart to enlarge.

Symptoms of an Enlarged Heart

In many cases, an enlarged heart may not present noticeable symptoms, especially in the early stages. However, as the condition progresses, individuals may experience a variety of symptoms, including:

  • Shortness of breath, particularly during exertion or when lying down
  • Fatigue and general weakness
  • Swelling (edema) in the legs, ankles, or feet
  • Palpitations, or feeling a rapid or irregular heartbeat
  • Dizziness or fainting
  • Chest pain or discomfort, particularly with activity
  • Coughing or wheezing, especially when lying flat
  • Unexpected weight gain due to fluid retention

If you or someone you know experiences these symptoms, it’s essential to seek medical attention to determine the underlying cause and initiate appropriate treatment.

Diagnosing Cardiomegaly

Accurate diagnosis of cardiomegaly typically involves a combination of physical examinations, imaging tests, and lab work. The following diagnostic tools are commonly used:

1. Chest X-Ray

A chest X-ray is often the first imaging test conducted, as it can reveal whether the heart is enlarged and by how much.

2. Echocardiogram

An echocardiogram uses sound waves to produce a detailed image of the heart, allowing doctors to see the size of the heart chambers and how well the heart is pumping blood.

3. Electrocardiogram (ECG/EKG)

An ECG records the electrical activity of the heart and can help detect abnormalities in the heart’s rhythm that might contribute to enlargement.

4. CT Scan or MRI

Advanced imaging techniques like CT scans or MRI provide even more detailed images of the heart’s structure and can help identify the cause of the enlargement.

5. Blood Tests

Blood tests can help identify underlying conditions, such as thyroid disease or infections, that may be contributing to cardiomegaly.

6. Cardiac Catheterization

In some cases, a catheter is inserted into the heart’s blood vessels to measure pressure inside the heart and evaluate coronary artery blockages.

Treatment Options for an Enlarged Heart

Treatment for an enlarged heart depends on the underlying cause and the severity of the condition. The primary goals of treatment are to address the root cause, reduce the heart’s workload, and prevent complications like heart failure.

1. Medications

Medications are often the first line of treatment for cardiomegaly and can include:

  • ACE inhibitors or ARBs, which help lower blood pressure and reduce the workload on the heart.
  • Beta-blockers, which slow the heart rate and reduce blood pressure.
  • Diuretics, which help remove excess fluid from the body, easing the heart’s workload.
  • Anticoagulants to prevent blood clots.
  • Antiarrhythmics to help manage abnormal heart rhythms.

2. Surgery or Medical Procedures

If medications are not sufficient, certain surgical procedures may be necessary, including:

  • Heart Valve Repair or Replacement to fix faulty valves that may be causing the heart to enlarge.
  • Coronary Artery Bypass Surgery for those with blocked arteries, improving blood flow to the heart muscle.
  • Left Ventricular Assist Device (LVAD), a mechanical pump that helps the heart pump blood more effectively.
  • Implantable Cardioverter-Defibrillator (ICD) to help manage dangerous heart rhythms.
  • Heart Transplant may be considered in severe cases where other treatments have failed.

3. Lifestyle Changes

Making certain lifestyle adjustments can also improve heart function and reduce the risk of further enlargement:

  • Maintain a healthy diet low in salt and saturated fats.
  • Regular physical activity can strengthen the heart and improve circulation.
  • Avoid smoking and limit alcohol intake.
  • Manage stress through relaxation techniques like yoga or meditation.
  • Monitor blood pressure and cholesterol levels regularly.

Complications of an Enlarged Heart

If left untreated, cardiomegaly can lead to serious complications, including:

  • Heart Failure: The heart’s inability to pump blood effectively can lead to fluid buildup in the lungs, legs, and abdomen.
  • Blood Clots: An enlarged heart is more prone to developing blood clots, which can lead to stroke or pulmonary embolism.
  • Cardiac Arrest or Sudden Death: Cardiomegaly increases the risk of life-threatening arrhythmias, which can cause sudden cardiac arrest.

Preventing Cardiomegaly

While some causes of cardiomegaly are genetic or beyond personal control, there are steps you can take to lower your risk of developing an enlarged heart:

  • Control blood pressure by maintaining a healthy diet and taking prescribed medications.
  • Exercise regularly to keep the heart strong and healthy.
  • Monitor cholesterol levels and manage conditions like diabetes that can strain the heart.
  • Avoid excessive alcohol and drug use.
  • See a doctor regularly to detect and treat any early signs of heart disease.

An enlarged heart is a serious condition that can lead to significant health problems if left untreated. However, with proper diagnosis, treatment, and lifestyle changes, many people with cardiomegaly can lead full, active lives. By understanding the causes, symptoms, and treatment options for cardiomegaly, you can take control of your heart health and reduce your risk of complications.

A picture of Giovanni B. Ciuffo, MD wearing his Mercy One doctor attire.

About the Author

Dr. Ciuffo’s practice is presently located in Las Vegas, NV. He practices with his colleagues at the Nevada Heart and Vascular Center and he serves as the Director of Cardiac Surgery at the University Medical Center of South Nevada.

Board Certified:
American Board of Surgery
American Board of Thoracic Surgery